Title

Increasing Average Fasting Insulin among Adolescents age 12-19, NHANES 2003-2010

Presenter Information

Erika Davis

Document Type

Oral Presentation

Location

SURC Ballroom C/D

Start Date

16-5-2013

End Date

16-5-2013

Abstract

Type 2 diabetes mellitus is increasingly becoming a public concern for the youth population. The aim of this study was to utilize the National Health and Examination Survey (NHANES) to assess the most recent trend of the risk factors for diabetes mellitus of adolescents fasting plasma glucose, glycohemoglobin (HbA1c) and fasting insulin. NHANES is a survey research program by Centers for Disease Control and Prevention that assesses health and nutritional status of the U.S. population. This study observed 2,716 adolescents from age 12 to 19 in the NHANES survey years 2003 to 2010. No significant difference in prevalence of diabetes and pre-diabetes was observed based on average fasting glucose values. However, HbA1c values showed a significant (p<0.05) shift towards higher HbA1c categories (three categories: 1) less than 5.7 percent; 2) 5.7 percent to 6.5 percent; 3) greater than 6.5 percent). In addition, there was a significant increase in average fasting insulin from 11.1 uU/mL in NHANES 03-06 to 12.6 uU/mL in NHANES 07-10. Higher average HbA1c suggests higher average blood sugar while higher fasting insulin suggests developing insulin resistance, which both are characteristics of type 2 diabetes mellitus. However, fasting glucose values did not significantly increase, possibly due to elevated production of insulin temporarily preventing fasting hyperglycemia. Despite a lack of significant difference in fasting glucose, the trend of increasing fasting insulin is a concern for future diabetes risk.

Poster Number

13

Faculty Mentor(s)

David Gee

Additional Mentoring Department

Nutrition, Exercise and Health Science

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May 16th, 11:30 AM May 16th, 2:00 PM

Increasing Average Fasting Insulin among Adolescents age 12-19, NHANES 2003-2010

SURC Ballroom C/D

Type 2 diabetes mellitus is increasingly becoming a public concern for the youth population. The aim of this study was to utilize the National Health and Examination Survey (NHANES) to assess the most recent trend of the risk factors for diabetes mellitus of adolescents fasting plasma glucose, glycohemoglobin (HbA1c) and fasting insulin. NHANES is a survey research program by Centers for Disease Control and Prevention that assesses health and nutritional status of the U.S. population. This study observed 2,716 adolescents from age 12 to 19 in the NHANES survey years 2003 to 2010. No significant difference in prevalence of diabetes and pre-diabetes was observed based on average fasting glucose values. However, HbA1c values showed a significant (p<0.05) shift towards higher HbA1c categories (three categories: 1) less than 5.7 percent; 2) 5.7 percent to 6.5 percent; 3) greater than 6.5 percent). In addition, there was a significant increase in average fasting insulin from 11.1 uU/mL in NHANES 03-06 to 12.6 uU/mL in NHANES 07-10. Higher average HbA1c suggests higher average blood sugar while higher fasting insulin suggests developing insulin resistance, which both are characteristics of type 2 diabetes mellitus. However, fasting glucose values did not significantly increase, possibly due to elevated production of insulin temporarily preventing fasting hyperglycemia. Despite a lack of significant difference in fasting glucose, the trend of increasing fasting insulin is a concern for future diabetes risk.