Document Type

Thesis

Date of Degree Completion

1970

Degree Name

Master of Science (MS)

Department

Chemistry

Committee Chair

John E. Meany

Second Committee Member

Leonard C. Duncan

Third Committee Member

Jerry L. Jones

Abstract

As early as sixty years ago, the existence of an enzyme from mammalian tissues which catalyzed the oxidation of xanthine and hypoxanthine was recognized. The name given the enzyme was derived from its earliest recognized action, hence xanthine oxidase. Although little is known about the biological functions of the enzyme, the high affinity shown for xanthine and hypoxanthine may indicate that these are the most significant substrates biologically.

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