Date of Degree Completion
Master of Science (MS)
Second Committee Member
Third Committee Member
The aim of this study was to investigate the effects of a history of weight cycling on insulin resistance (IR) utilizing the 2015-2020 NHANES database. A value greater than 3.2 for homeostatic model assessment of insulin resistance (HOMA-IR) was used to define IR. No study to date has examined the weight cycling question since its application in the NHANES 2015-2016 cycle year. RESULTS 53% of the total 4100 participants reported weight cycling at least once and 33% of the total were classified as having IR. Prevalence of IR and obesity were highest amongst those who weight cycled 3 times or more, and diabetics were more likely to weight cycle than non-diabetics. A positive association was found for history of weight cycling and average BMI, maximum historical BMI, waist circumference, HOMA-IR, and fasting insulin levels. Simple logistic regression showed that weight cycling 3 times or more substantially increased the odds of becoming obese (OR 4.42, PP
Burke, Jessica Claire, "Investigating the Effects of Body Weight Fluctuations on Insulin Resistance in Adults: a NHANES Study" (2022). All Master's Theses. 1746.