A familial X-22 translocation with an extra X chromosome

Document Type

Article

Department or Administrative Unit

Biological Sciences

Publication Date

11-1974

Abstract

The occurrence of X-autosome translocations in man is rather infrequently observed. This type of rearrangement is of particular interest to geneticists because of the variety of late-labeling patterns which occur as a result of inactivation of the X chromosome and because of the role this inactivation may play with respect to clinical abnormalities.

We report in this paper a family in which the long arm of a no. 22 chromosome has been translocated to the long arm of an X chromosome. In addition to the translocation, some members of the kinship also possess an extra X chromosome.

Comments

This article was originally published in American Journal of Human Genetics. The full-text article from the publisher can be found here.

Due to copyright restrictions, this article is not available for free download from ScholarWorks @ CWU.

Journal

American Journal of Human Genetics

Copyright

© 1974 by the American Society of Human Genetics. All rights reserved.

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