Copper-catalyzed regioselective dehydrogenative alkoxylation of morpholinonyl alkenols: application to the synthesis of spirotricyclic dihydropyrans and of trans-fused bicyclic morpholines

Authors

Timothy K. Beng, Central Washington UniversityFollow
Megan Bauder, Central Washington University
Morgan J. Rodriguez, Central Washington University
Antonio Moreno, Central Washington University

Document Type

Article

Department or Administrative Unit

Chemistry

Publication Date

9-20-2018

Abstract

A base-free, regioselective and atom-economical approach to aryl-substituted as well as morpholine-fused dihydropyrans, by Cu-catalyzed intramolecular dehydrogenative alkoxylation of allylic morpholinols, is described. Spirotricyclic dihydropyrans are affordable after ring-closing metathesis.

Comments

This article was originally published in New Journal of Chemistry. The full-text article from the publisher can be found here.

Due to copyright restrictions, this article is not available for free download from ScholarWorks @ CWU.

Recommended Citation

Beng, T.K., Bauder, M., Rodriguez, M.J., & Moreno, A. (2018). Copper-catalyzed regioselective dehydrogenative alkoxylation of morpholinonyl alkenols: application to the synthesis of spirotricyclic dihydropyrans and of trans-fused bicyclic morpholines. New Journal of Chemistry 42, 16451-16455. https://doi.org/10.1039/C8NJ03890B

Journal

​New Journal of Chemistry