Investigating the Effects of Body Weight Fluctuations on Insulin Resistance in Adults: an NHANES Study

Document Type

Poster

Event Website

https://source2022.sched.com/

Start Date

16-5-2022

End Date

16-5-2022

Keywords

Weight Cycling, HOMA-IR, Obesity

Abstract

The aim of this study was to investigate the effects of weight cycling on insulin resistance (IR) utilizing the 2015-2020 NHANES database. A value greater than 3.2 for homeostatic model assessment of insulin resistance (HOMA-IR) was used to define IR. No study to date has examined the weight cycling question since its application in 2015. RESULTS: 53% of the total 4100 participants reported weight cycling at least once, and 33% of the total were classified as having IR. Prevalence of IR and obesity were highest amongst those who weight cycled three times or more, and diabetics were more likely to weight cycle than non-diabetics. A positive association was found for history of weight cycling and average BMI, maximum historical BMI, waist circumference, and HOMA-IR. Simple logistic regression showed that weight cycling three times or more substantially increased the odds of becoming obese (OR 4.415, p

Faculty Mentor(s)

Dana Ogan, David Gee, Susan Hawk

Department/Program

Food Science and Nutrition

Additional Mentoring Department

Food Science and Nutrition

Additional Mentoring Department

Graduate Studies

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May 16th, 12:00 AM May 16th, 12:00 AM

Investigating the Effects of Body Weight Fluctuations on Insulin Resistance in Adults: an NHANES Study

The aim of this study was to investigate the effects of weight cycling on insulin resistance (IR) utilizing the 2015-2020 NHANES database. A value greater than 3.2 for homeostatic model assessment of insulin resistance (HOMA-IR) was used to define IR. No study to date has examined the weight cycling question since its application in 2015. RESULTS: 53% of the total 4100 participants reported weight cycling at least once, and 33% of the total were classified as having IR. Prevalence of IR and obesity were highest amongst those who weight cycled three times or more, and diabetics were more likely to weight cycle than non-diabetics. A positive association was found for history of weight cycling and average BMI, maximum historical BMI, waist circumference, and HOMA-IR. Simple logistic regression showed that weight cycling three times or more substantially increased the odds of becoming obese (OR 4.415, p

https://digitalcommons.cwu.edu/source/2022/CEPS/7