Modular access to vicinally functionalized allylic (thio)morpholinonates and piperidinonates by substrate-controlled annulation of 1,3-azadienes with hexacyclic anhydrides

Authors

Hannah Braunstein, Central Washington University
Spencer Langevin, Central Washington University
Monique Khim, Central Washington University
Jonathan Adamson, Central Washington University
Katie Hovenkotter, Central Washington University
Lindsey Kotlarz, Central Washington University
Brandon Mansker, Central Washington University
Timothy K. Beng, Central Washington UniversityFollow

Document Type

Article

Department or Administrative Unit

Chemistry

Publication Date

10-7-2016

Abstract

A modular substrate-controlled hexannulation of inherently promiscuous 1,3-azadienes with hexacyclic anhydrides, which affords versatile vicinally functionalized allylic lactams, in high yields, regio- and stereoselectivities is described.

Comments

This article was originally published in Organic & Biomolecular Chemistry. The full-text article from the publisher can be found here.

Due to copyright restrictions, this article is not available for free download from ScholarWorks @ CWU.

Recommended Citation

Braunstein, H., Langevin, S., Khim, M., Adamson, J., Hovenkotter, K., Kotlarz, L., Mansker, B., & Beng, T. K. (2016). Modular access to vicinally functionalized allylic (thio)morpholinonates and piperidinonates by substrate-controlled annulation of 1,3-azadienes with hexacyclic anhydrides. Organic & Biomolecular Chemistry, 14(37), 8864–8872. https://doi.org/10.1039/c6ob01526c

Journal

Organic & Biomolecular Chemistry

Rights

© 2016 Royal Society of Chemistry.