Iridium-catalyzed α-alkynylation of cyclic nonaromatic eneformamides: application to the synthesis of azapolycyclic architectures

Authors

Timothy K. Beng, Central Washington UniversityFollow
Francine Wanjiku, Central Washington University

Department or Administrative Unit

Chemistry

Document Type

Article

Publication Date

2-20-2019

Journal

New Journal of Chemistry

Abstract

A modular, regioselective, step-economical, and chelation-assisted dehydrogenative alkynylation of cyclic nonaromatic eneformamides with terminal alkynes, under iridium catalysis, is described. The versatile eneformamidynes have been skeletally remodelled to other relevant architectures, including saturated cyclic amines and azabicyclic amines.

Comments

This article was originally published in New Journal of Chemistry. The full-text article from the publisher can be found here.

Due to copyright restrictions, this article is not available for free download from ScholarWorks @ CWU.

Recommended Citation

Beng, T. K., & Wanjiku, F. (2019). Iridium-catalyzed α-alkynylation of cyclic nonaromatic eneformamides: application to the synthesis of azapolycyclic architectures. New Journal of Chemistry, 43(12), 4664–4668. https://doi.org/10.1039/c9nj00003h